Microbial virulence

The ability of bacteria to cause diseases is described in terms of the number of infecting bacteria, the route of entry into the body, the effects of host defense mechanisms, and intrinsic characteristics of the bacteria called virulence factors. Virus virulence factors allow it to replicate, modify host defenses, allow it to spread within the host and are toxic to the host. During the process of infection, virulence factors of microorganisms combat with the defense mechanism of the host. If virulence factors overcome the defense mechanism of the host, infection is established otherwise microorganisms are eliminated from the host. Pathogenicity of microorganism is determined by nature and type of its virulence effect.

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