Mechanisms of Antibiotic Resistance

Mechanisms of antibiotic resistance refer to the various ways in which bacteria evolve and adapt to become resistant to the effects of antibiotics. One common mechanism is through the alteration of bacterial targets, where mutations or modifications in cellular structures make antibiotics less effective. Another mechanism involves the production of enzymes, such as beta-lactamases, that degrade or inactivate antibiotics before they can exert their antibacterial effects. Additionally, bacteria can develop efflux pumps that actively remove antibiotics from inside the cell, reducing their concentration and efficacy.


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