Antimicrobial and Antibacterial Agents

Antimicrobial Pathogens : Alternative Approaches

Infections of antibiotic-resistant pathogens cause an ever-increasing threat to mankind. The investigation of novel approaches to deal with the antimicrobial resistance crisis should be part of global response to present drawback if an untimely reversion to the pre-penicillin era of medicine is to be avoided. One such promising avenue of analysis involves so-called antibiotic resistance breakers (ARBs), capable of re-sensitising resistant bacteria to antibiotics. Multidrug-resistant bacteria are getting more common and due to their multiplicity of mechanisms, they are frequently resistant to  several if not all of the current antibiotics. This intimidating spectre has been the target of several research efforts into conventional antibiotics and alternative approaches. Bacteria have developed the capability to  supply structured communities (or cluster of cells) via adherence to surface to form biofilms that facilitate or prolong their survival beneath extreme environmental condition.